SAMP8小鼠 | AD模型61
发表时间:2023-04-21 09:53作者:郑小薯、宋小饱 别名:SAMP-8, SAM-P/8, SAM-P8 物种:小鼠 编辑类型:自发突变 疾病相关:阿尔茨海默症 遗传背景:AKR/J,疑似杂交了未知品系 概要 神经病理 认知/行为 参考资料 Alzforum资料:www.alzforum.org/research-models/senescence-accelerated-mouse-samp8 Inotiv资料:www.inotivco.com/model/samp8-tahsd Amano T, et al. Increased expression of cathepsins E and D in reactive microglial cells associated with spongiform degeneration in the brain stem of senescence-accelerated mouse.Exp Neurol. 1995 Dec;136(2):171-82. Karasawa N, et al. Immunocytochemical study of catecholaminergic neurons in the senescence-accelerated mouse (SAM-P8) brain.J Neural Transm. 1997;104(11-12):1267-75. Miyamoto M, et al. Age-related changes in learning and memory in the senescence-accelerated mouse (SAM).Physiol Behav. 1986;38(3):399-406. Miyamoto M, et al. Senescence-accelerated mouse (SAM): age-related reduced anxiety-like behavior in the SAM-P/8 strain.Physiol Behav. 1992 May;51(5):979-85. Miyamoto M. Characteristics of age-related behavioral changes in senescence-accelerated mouse SAMP8 and SAMP10.Exp Gerontol. 1997 Jan-Apr;32(1-2):139-48. Yagi H, et al. Spontaneous spongy degeneration of the brain stem in SAM-P/8 mice, a newly developed memory-deficient strain.J Neuropathol Exp Neurol. 1989 Sep;48(5):577-90. |